I agree the Nano takes a bit more fiddling. But with that effort I think I get a bigger sound.

The only drawback is that I like the vocal pre-amp in the Compact better than the single input on the Nano.

Here's the other thing. I've A/B'd running the keyboard through a single Compact with one input and running the keyboard(two inputs out)through the Nano with it's two inputs. Granted the Nano is not stereo at this point but the sound coming from the Nano with it's two inputs really sounded much more full(to my ears anyway) than the single input to the Compact.

That sound two inputs into an amp from the keyboard convinced me that if I use one amp it will be the Nano. If I use two amps, then I think both the Bose and Nano work.