Can I say what might be construed as a silly answer ? Never. I think I have it right and then do a gig and something comes up and I have that moment where I think " What was I thinking on this ?" I keep a small notepad with me and if and when I get a chance I notate what needs to be worked on at home. I made so many changes to things its and endless process. EX: I "thought" I had a great drum sound so put it in a bunch of Styles. Nope, back home its time to change them again And on and on.
Better answer, keep it simple so you can you can do your main tunes comfortably and expand from there.
Bill in SC --- Roland BK9 (2) Roland BK7M, Roland PK5 Pedals, Roland FP90, Roland CM30 (2), JBL Eon Ones (2) JBL 610 Monitor, Behringer Sub, EV mics, Apple iPad (2) Behringer DJ mixer