I think you can, but it's an either/or thing. You can't say substitute a different snare in the audio loop, or move it's kick to a slightly different pattern, and so far, as far as I can remember, nobody has posted an Audya demo where they proudly pointed to the drums and went 'that's the MIDI drums!'. So far, it's only been the Live Loops that have been showcased.

For me, it's primarily about having the drum samples recorded ambiently. Once that is done (and the sample have at LEAST four or more velocity cross-switches), then a well played MIDI pattern stands a real good chance of being mistaken for the real thing.
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An arranger is just a tool. What matters is what you build with it..!