I am running a hybrid rig. I have a KN7000 lower, and a controller keyboard on top to run my Muse Receptor.
The Receptor is in my rack, loaded with B4II, Colossus, and Kontakt2. I use it only for solo voices at this point. I haven't gotten into styles, loops, or sequencing yet. The Receptor is a 2.5MHZ, 180 GB HD, with 2 GB RAM in a rack configuration.
Audya76, Yamaha S910, Technics KN7000, vArranger