Kind of, rather busy in real life...

I connect my ipad directly over USB for midi.. to my keyboards..
I have a usb switch (powered) connected to the lightning of my ipad
I also have a pro-audio interface connected (NI komplete audio 6) to my keys for audio in and out.

I don’t experience any lag..

I am not using the yamaha part..
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Yamaha Genos, Roland Jupiter 80, Ipad pro.

http://keyszone.boards.net