I keep it simple in regards to harmonizers...less is more, so to speak.
I mainly use the VH2 harmonizer in my Tyros4 as a Vocoder, but sometimes we'll use it in the studio, but sparingly. I use some of Dan Rymut's (aka big741.1) settings for the VH2 and they work really well.
In the studio vocal harmonies are generally done as overdubs, but I'd have no problem using my T4's VH2 on a "live" gig; again, less is more and being comfortable and adept with using your mic/harmonizer combination is paramount to success. I never have expected things to work without any "adjustments". I've been very successful with using a vintage Electro-Voice RE-15 for both vocals and Vocoding.
The VH2's biggest improvement over the old is that it doesn't have a glitch if you switch on the harmony while singing a note.
I'm lucky in regards to playing with other performers due to the local jam sessions we have, and, quite often we'll have a guest player who usually brings something new to the table.
As we get older, and also as the music scene changes, "live" playing in a group is not always possible, and/or profitable, so luckily there are those clever enough to use the, otherwise designed first as a "home keyboard", Arranger as a tool for professional one-man-band performing.
It keeps the player working...that's the main thing.
Ian
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Yamaha Tyros4, Yamaha MS-60S Powered Monitors(2), Yamaha CS-01, Yamaha TQ-5, Yamaha PSR-S775.