I spoke with Bose technical gurus today and they said there is no difference in running mono or RCA stereo. They did encourage to experiment for myself and I may hear a difference.
_________________________
Yamaha 920 / Yamaha DGX-670 / Maui 5 Go (2) / Senn e935 / Sony C80 / Tascam DP24sd / ATEM Mini Pro switcher (studio)