E50 and 60 don't have any harmonizer... G70 and E80 only.
E50 and 60 seem to have all the Cover, Makeup Tools and Database functions that I saw on the Discover5.
To be honest, if you want GREAT SMF playback and editing tools AND an arranger, you can't go wrong with the E and G series. Roland has always pretty much led the pack in SMF playback....
I'd still like to hear what the D5 did that can't be done on an E50/60/80/G70... (other than the lack of harmonizer on the lower end models)
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An arranger is just a tool. What matters is what you build with it..!