You should listen carefully to guitar music when you hear it now to examine how the different sounds are applied.
Clean guitar sounds that have that compressed Stratocaster twang, and also acoustic guitar sounds are best suited to rhythmic chordal and arpeggiated patterns (simulating rhythm and picking styles). This is due to the limited sustain these sounds have.
Distorted and Overdrive (ie. very distorted ) tend to have much more sustain and lend themselves to both 1st and 5th powerchords as well as mono lead solos. Feedback guitar is pretty much the same sound as Overdrive but morphes into a feedback wave after the note has been sustained. Use your pitchwheel when the feedback starts to whistle for that Van Halen whammy bar emulation.
[This message has been edited by Nigel (edited 07-31-2002).]