What operating system are you running? EDM will not run under NT4, Win2000, or (presumably) XP due to the restriction of BIOS calls.

If you are launching it from Win9x and you are using a shortcut to launch it, make sure you have a valid CMD Line and Working directory entered in the properties page of the shortcut.

e.g.
CMD: C:\EDM\EDM.EXE
Working: C:\EDM

Hope this helps...