I use a Ketron X3 with two different keyboard controllers. One very slim lightweight 61 note job for playing gigs with and an 88 note fully weighted one for home and recording use. It's true that there are more connections to set up and I also have to use the extender arms on my X-Stand at gigs but the flexibility this set up gives outweighs a few extra mins setup time.
I'm lucky in that the Ketron gives me exactly what I want out of an arranger 'cos there aint too many module ones around now.
KF