I am not familiar with the meaning of 'hands on' advantage, but I control the B4 from the PSR-740 registration buttons. It also responds directly to the foot-pedal volume control. So I don't have to really do anything at the computer screen, except if I want to experiment with it. On one of the presets, in fact, I set an XG voice simultaneous with the B4. That feature alone multiplies voice sounds to the zellions. There are very nice sounds that way buy I settled for just a few. Of course, the auto-accomp from the 740 is being used also. For very little money one gets even better than a B3 (in a way) because it responds to MIDI and to the PSR. Initially I had planned to buy slider controlls like Peavy. Uncle Dave helped me with info. But I settled with the use of the presets. By pushing the preset, all of the parameters selected at the B4 are activated, including amplifier distortions (if you like it), vibratos, etc., you name it. Then for playing it the volume foot pedal IS the expression pedal which I never used fully untill I discovered it is a must for playing the B4. To do that you must create a SILENT voice in the PSR, which was a trick in itself.