sbenno,
plugzilla is $3200 box "turnkey", but CPU expander from PC tower+ethernet is $1000 plus system administrator work (OS installing than tuning, plugin host instolling, network routing etc. + the same tuning work from Mediastation part).
Musicians are about music, not system administration. Personally I'll prefer simply take Mediastation plus expansion kit (box, card, etc.) that I will not be tuning and tweaking from the beginning.
I think it can be bootable hard drive that I can install to my computer, connect computer to Mediastation via ethernet and boot from this hard drive. But after that it should work immediately -- and it should not be tweaking of any configuration files!
It should be SOLUTION but not SERVER with API. It should be zero time setup of VST-powered Mediastation. Better of all it should be Mediastation with hardware VST-option, not external CPU expander...
This is why Windows win from Unix 10 years ago. Windows was capable of doing 3 things immediately from boot. Unix was capable of doing 300 things after configuration and tweaking and tuning.
Mediastation and CPU expander should be like devices, not like software systems.
I am afraid that from possibility of VST playing from Mediastation to robust VST turn-key Mediastation solution will be couple of years...
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Roland G-70, Korg M3-73 with Radius, Roland Handsonic HPD-15