Yes, I've been able to use the lh buttons on an ELKA midi accordion ctlr to control the One Man Band (OMB71) arranger software on a PC. You can run OMB on a laptop and have it play thru a module. At least then you'd have the ability to 'arrange' your performances live (repeats, multiple choruses) rather than having to follow an mp3 or SMF.

If you go this route, you may want to check out the hi end sound modules such as the Korg Triton rack, Yamaha Motif rack, and Roland xv5050 rack. These may have better sound quality than the table top midi modules (SC88, MU100) that are marketed as playback modules.