Last week a similar thing happened to me. The volume level really faded in the middle of a song. I turned up he master vol on the mixer and carried on. It came back after a minute or two, and I hastily had to turn the vol back.
The thing happened again later, and this time I jiggled with the cables into the mixer. And guess what, I had obviously, in my hurry to set up, not properly seated one of the speaker cables. Phew!
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Graham, Korg Pa1000, Korg G1 Air, Countryman E6, Roland BA330, 2 x Roland CM-30, , Mackie SRM150