Possibly by using something naff like Quicktime Instruments, or something like that, but let's face it, even a MODERN TOTL laptop has some pretty severe issues running a complete soft arranger and sounds, effects and everything else we expect in a hardware arranger, to the quality of something like the T4 or PA3.

Otherwise, we'd all be using them!
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An arranger is just a tool. What matters is what you build with it..!