I have 2 San Disk cruzers with the U3 that do not work on my Tyros, though I have not tried downloading the uninstaller that Jim mentions. Glad I read the post and will try to get rid of the remaining U3 stuff.
The U3 sticks are also troublesome on my VR3 FM transmitter that I use to play music in the car over the FM radio. Sometimes they work and then just cut out. I also occasionally have trouble with the store brand Best Buy sticks I have ( both of them with no U3 ). None of my other sticks give me any problems at all.
There are enough inexpensive usb sticks out there that don't have the U3 system. I'd recommend staying away from the ones that do, unless you don't mind the extra work in downloading and using an uninstaller.
AJ
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AJ