In my business we use UPS to ship around the country...probably 5 shipments a day. In the 17 years we have used them, we have never lost a shipment. On-line tracking capabilities make it possible to find out exactly when something was delivered and who signed for it. This is particularly important if a shipment goes to the receiving department at a large organization and gets lost in the stack. The receiver can go directly to the person who signed for the package.
We do a lot of shipping, and check rates every few months. UPS is much less expensive.
Russ