Scott...
Its all in the years of experience, each job is different, each room is different & requires a special setup. Use the sub for dancing gigs, use the stands to cover a bigger area with your satelites and speakers, shoot the sound above a big crowd. sometime you only need one stand and one speaker on the floor, sometimes no stands in a small dinner venue..mixin up your setup is part of being an entertainer, there are no rules....
good luck