Tony you may need to go into the Control Panel/Sounds and Audio Devices click Device Volume "Advanced" and make sure your "Play Control is not muting any necessary Formats, ie., Wav/MP3, etc. If it is muted 'un-tick' it. Under the "Audio" tab make sure your device for Playback is your actual Sound Card. Same goes for Midi Playback device too and likewise under the "Voice" tab. Then make sure "Use only default devices" is checked under the "Audio" tab.

See if that helps.

Best regards,
Mike