Yamaha's O1x looks very promising, but seems to rely much on their mLan interface which has not become widely accepted outside of Yamaha-world (don't get me started on why it's not on any of their arrangers...). And the 01x already has direct competition from Tascam:
http://www.tascam.com/products/computer_recording/fw1884/index.php

There are a slew of Firewire and USB 2.0 audio interfaces coming out this summer so the real question is whether you really need a $1700 mixer/control surface. Hmmmm...