I think "start again" is good advice!

And whilst I don't know a thing about the software you are using, I feel a mini-rant coming on, aimed at all the "its broken, please help" postings...

What does "not working" actually mean? Do the software packages now fail to initialise at all? Or do they start up and then not recognise the keyboard that is attached to the computer? What interfaces are they using - Serial? Midi? "To Host" serial Cable? USB? Firewire?

This sort of information makes "remote" advice much more meaningful.

Hope you get this sorted. It seems very strange that the software interacts in this way.