Due to that situation tried many things. The height is very important. But even at the correct hight, the mouse is still not a correct interface for prolongued use. Have switched to a pen-and tablet interface, AIPTEK brand. I click the pen buttons with the thumb. Scrolling with the wheel mouse looked nice, but it brought pain to the index finger. Now the pen does the scrolling up and down with a minimum of effort, and it is very natural. The logical interface would have been a pen. But they designed the interface with old electronics inside a small wood box simply because of space and so the mouse was born. It was not meant for so much use as now we give it, but luckily the pen and tablets are now affordable. Eventually, the laptop screen will be the tablet. A wrist brace will help heal the problem. The skate-board protection gloves kids use are a good substitute. Careful, if prolonged, surgery is almost the only way to remove fibrosis there. Good luck.