Beakybird, I'm not sure I understand your question, but if you are trying to compare the use of a USB to MIDI cable vs a game port to MIDI cable (that could plug into the game port of a PC sound card or an I/O card), there is no real difference. Midi is Midi no matter how it is connected between the keyboard and the PC. Most newer laptops have no game port or other midi interface support and the USB interface is the only thing available that I am aware of. Recording digital audio via the analog audio in/out of a sound card is an entirely different thing and is not a midi issue.